Neuropathology & Brain Tumor Pathology

Expert neuropathologic consultation for complex brain, spinal cord, and peripheral nerve cases. We connect histopathology, molecular signatures, and clinical course, grounded in decades of academic leadership and bench-to-bedside research in glioma invasion and angiogenesis.

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Pathology Leadership

Led by a board-certified neuropathologist who directs a neuro-oncology laboratory and has shaped modern understanding of glioma invasion, hypoxia response, and tumor vascular biology.

Neuropathology Expert Witness

Board-Certified Neuropathologist | Division Chief | Director, Molecular Neuro-Oncology Laboratory

A nationally recognized neuropathologist with more than three decades at major academic medical centers, serving as professor of pathology and neurosurgery, division chief of neuropathology, and director of a molecular neuro-oncology laboratory. Licensed and dual-board certified in Anatomic Pathology and Neuropathology, with thousands of brain and spinal tumor specimens interpreted while mentoring residents, fellows, and junior faculty.

Research pioneered models of glioma invasion and angiogenesis, introduced the concept of vascular involution, and demonstrated how hypoxia-inducible pathways (HIF-1alpha/CXCR4) drive tumor spread. Co-developed predictive MR algorithms for low-grade gliomas and is repeatedly recognized for teaching and scholarship with national awards.

Board-Certified & Licensed

Medical license; American Board of Pathology certifications in Anatomic Pathology and Neuropathology.

Academic Leadership

Professor of Pathology and Neurosurgery; Chief of Neuropathology; long-standing neuropathologist at major academic medical centers.

Translational Neuro-Oncology

Directs a molecular neuro-oncology laboratory focused on glioma angiogenesis, invasion, and hypoxia signaling, with extensive publication and editorial-board service.

Recognized Educator

Recipient of multiple teaching honors and national recognition for neuro-oncology scholarship.

Training. B.S. in mathematics and biology; M.D.; Ph.D. in neurology and neurosurgery; internship in general surgery; residency in anatomic pathology; fellowships in neuropathology and cell biology at leading academic medical centers.

Focused Neuropathology Services

Clear, defensible opinions for litigation, regulatory review, and complex clinical questions.

Brain & Spinal Tumor Diagnostics

Comprehensive histopathology for gliomas, meningiomas, pituitary tumors, pediatric brain tumors, and metastatic disease with correlation to clinical and imaging findings.

Molecular & Hypoxia Pathways

Interpretation of hypoxia-inducible signaling (HIF-1alpha/CXCR4), angiogenic markers, and related molecular assays to clarify mechanisms of invasion and treatment response.

Treatment Effect & Recurrence Analysis

Evaluation of surgical margins, radiation/chemotherapy effect, anti-angiogenic therapy patterns, and progression versus pseudoprogression in high-grade gliomas.

Expert Testimony & Reporting

Board-certified expert witness testimony, deposition support, and detailed reports that integrate pathology, molecular data, and peer-reviewed literature.

Research-Grade Review

Consultative review of experimental models, including glioma invasion assays and angiogenesis studies, informed by decades of laboratory leadership.

Education & Case Conferences

Case-based teaching for legal teams and medical stakeholders, translating complex neuropathology into clear, courtroom-ready narratives.

Representative Case Themes

Examples of the neuropathology issues we address for plaintiff and defense teams.

We frequently consult on:

  • Glioblastoma growth patterns, invasion pathways, and vascular proliferation.
  • Low-grade glioma progression, treatment response, and surveillance interpretation.
  • Angiogenesis and hypoxia-driven change in gliomas, including HIF-1alpha/CXCR4 dynamics.
  • Pediatric brain tumors and diffuse intrinsic pontine gliomas, with clinicopathologic correlation.
  • Therapy-related effects and recurrence in meningiomas, vestibular schwannomas, and pituitary tumors.
  • Molecular classification disputes, including IDH status, methylation profiling, and emerging biomarkers.
  • Cause-of-death and central nervous system pathology in complex autopsy cases.

Put Neuropathology Evidence on Firm Ground

Engage board-certified neuropathology expertise that integrates histology, molecular drivers, and clinical context.